Peripheral Resistance to Thyroid Hormones
نویسندگان
چکیده
منابع مشابه
Thyroid Hormones and Peripheral Nerve Regeneration
Peripheral nerve regeneration is a unique process in which cellular rather than tissue response is involved. Depending on the extent and proximity of the lesion and the age and type of the neuronal soma, the cell body may either initiate a reparative response or may die. Microsurgical intervention may alter the prognosis after a peripheral nerve injury but to a certain extent. By altering the b...
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Peripheral metabolism of thyroid hormones is a critical component of the impact these hormones have on intracellular function. Thyroid hormones can be metabolized in peripheral tissue by deiodination, conjugation, deamination, and decarboxylation enzyme reactions. Therefore, alterations in these metabolic pathways might significantly impact the quantity of specific thyroid hormone metabolites i...
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OBJECTIVE To examine the relation between baseline measurements of thyroid function and response to selective serotonin reuptake inhibitors (SSRIs) and to consider the effect of these antidepressants on thyroid hormone levels. METHODS Nineteen subjects with major depression, but without a history of thyroid treatment or lithium treatment, were treated openly with either sertraline or fluoxeti...
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Thyroid hormone is long known as an important regulator of metabolism. It exerts general effects such as increased cycling of metabolites and stimulation of ATP turnover in spite of reduced efficiency of oxidative phosphorylation, but also very specific effects in peripheral tissues. This article reviews the most relevant metabolic effects of thyroid hormone in peripheral tissues, including the...
متن کاملResistance of peripheral tissues and pituitary to thyroid hormone.
We describe a 29-year-old male with thyroid hormone resistance. He was first seen because of a goiter, and was considered to have hyperthyroid Graves' disease. Despite subtotal thyroidectomy followed by radioiodine therapy, serum thyroxine levels were elevated with high serum TSH levels. Baseline thyroid function showed serum thyroxine of 16.6 micrograms/dl, free thyroxine of 4.60 ng/dl, triiod...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 1985
ISSN: 0025-6196
DOI: 10.1016/s0025-6196(12)60543-6